Repetitive Transcranial Magnetic Stimulation (rTMS)

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rTMS Study

Brain Stimulation for Hand Recovery Following Stroke

Clinic Location

Physical Medicine & Rehabilitation Clinic
M Health Clinics and Surgery Center
909 Fulton St. SE
Minneapolis, MN 55454 

Directions & Parking

Additional Information

If you would like more information, please call 612-676-5698.

The Brain Following Stroke

Neurons (brain cells) that lose their blood supply for very long because of a stroke become destroyed, creating an infarct, or an obstruction. If the infarcted region is in the area of the brain that controls hand movement, or its pathways, hand function suffers. As if the stroke itself were not bad enough, the brain -- while reorganizing in response to the stroke -- can have an effect on surviving neurons that are close to the infarct. These surviving neurons can then become suppressed, worsening the paralysis. Rehabilitation cannot bring destroyed neurons back to life, but it can raise the excitability of suppressed neurons and thereby improve hand function. Repetitive transcranial magnetic stimulation (rTMS) is a procedure used in combination with rehabilitation that, in some people, can improve hand recovery.

What is rTMS?

rTMS involves a device delivering magnetic stimuli to the outside of the head that pass through the skull and creates either inhibitory (calming) or excitatory (excite) effects on underlying brain neurons, depending on the stimulation frequency. Inhibitory (low frequency) stimulation can be applied to the non-stroke side of the brain to suppress signals coming from that side that inhibit surviving neurons in the other side of the brain that had the stroke. Thus, in this case, the rTMS would have the strange but true effect of “inhibiting the inhibition." By quieting the signals sent from the non-stroke side of the brain, the neurons in the stroke-side of the brain can become excited and contribute again to hand function. Alternatively, high frequency stimulation can be applied to the stroke hemisphere to yield a more direct excitatory effect.

In either approach, the patient sits in a chair and EMG electrodes are applied to the skin over certain hand muscles. While monitoring responses on an EMG screen, we use the TMS device to search for the best location and lowest intensity of stimulation that delivers a reasonable response. During this a clicking noise is heard and a painless tapping sensation is felt on the scalp. Once the best location and intensity are confirmed, treatment then occurs for 10-20 minutes followed by hand exercises for 30-45 minutes.


Criteria for Receiving rTMS for Hand Recovery Following Stroke

Criteria for Receiving rTMS for Hand Recovery Following Stroke

  • Finished with their initial rehabilitation
  • Have at least some active finger motion
  • No metal in the head with the exception of dental metal
  • No indwelling medical devices
  • No seizure within 2 years
  • Certain medications may not allow a person to receive this treatment
  • An MD referral is needed

Benefits & Risks

Benefits & Risks

The videos below show the benefit gained by one person who received rTMS combined with physical therapy.
 
BEFORE rTMS TREATMENT


 
AFTER rTMS TREATMENT



However, not every person will benefit from rTMS. There are no guarantees of improved recovery but certain characteristics increase the likelihood of a beneficial outcome, such as presence of active finger motion, stroke location, time since stroke, and absence of medical depression.
 
The primary risk of rTMS is a seizure. We have taken measures in our protocol to minimize this risk but the risk is still present. Other risks include headache, impaired hearing, impaired concentration, tiredness, lightheadedness, and mood change. All these are rare.

What is the Cost of rTMS?

What is the Cost of rTMS?

At this early innovative stage in rehabilitation, Medicare does not yet cover the expense and so patients would have to pay privately for the service. The service (10 treatments) costs a total of $2395. (Some assistance may be available to patients that are not able to afford the care on their own.)

Support rTMS Treatment

Since insurance is not currently covering treatment, we welcome support to provide assistance to those patients that cannot afford the treatments. Please click here to find out how you can support this effort.